The Port of Ensenada is located in the northwest corner of Mexico, in the state of Baja California, a strategic point in the Pacific basin, only 110 kilometers from the border of Mexico with the United States of America and in the head of the Municipality of Ensenada, bordering to the north with the states of California and Arizona and to the south with Baja California Sur, to the east with Sonora and to the west with the Pacific Ocean. Its geographic position is located at coordinates 31 51'30" North Latitude and 116 38'00" West Longitude.

The municipality of Ensenada has an extension of coastline of 1,114.89 kilometers, which represents more than 80.8% of the total coastline of the State; it also has 74,800 hectares of coastal lagoons, suitable for aquaculture.

For overland movement of cargo to and from the port, the three most important routes are the Tijuana-Ensenada highway and the federal highways Tijuana-Ensenada and Tecate-Ensenada. The highway is of high specifications (4 lanes and 2 bodies) and the largest cargo flows are transported through it. The three roads indicated are the basic links to communicate the Port with the main road network of the United States of America.